معرفی
J. Martin Bollinger Jr. is the Russell and Mildred Marker Professor of Natural Products Chemistry and a Professor in the Department of Biochemistry and Molecular Biology at The Pennsylvania State University, affiliated with the Eberly College of Science. His research focuses on metalloenzymes and metallocofactor assembly mechanisms, particularly di-iron clusters and iron-sulfur (FeS) clusters. He leads the Bollinger-Krebs Group, collaborating on projects involving spectroscopic and biophysical techniques to study enzyme mechanisms.
Research interests include understanding how di-iron clusters 'tune' reactivity across diverse oxidation reactions (e.g., methane monooxygenase, ribonucleotide reductase) and elucidating FeS cluster assembly pathways in proteins. Methods employed include rapid kinetic assays, EPR, EXAFS, and X-ray crystallography. Current projects explore dynamic FeS cluster regulation in transcription and enzyme stability.
No specific awards or grants are listed, but his work emphasizes interdisciplinary collaboration with groups at Penn State and other institutions. The lab’s future directions aim to advance biomimetic catalyst design and FeS biogenesis mechanisms.
