Isaiah (Shy) Arkin

Prof. Isaiah (Shy) Arkin is a Professor in the Department of Biological Chemistry at the Hebrew University of Jerusalem's Silberman Institute of Life Sciences. His research focuses on the structural biology of membrane proteins, particularly viral ion channels and pumps, and the development of antiviral therapies targeting SARS-CoV-2 and influenza viruses. He employs advanced techniques including FTIR spectroscopy, molecular dynamics simulations, and statistical analysis.

Research Interests:

• Computational and experimental structural biology of membrane proteins
• Structure-function relationships in viral ion channels
• Antiviral drug discovery
• Development of novel experimental/computational methodologies

Prof. Arkin has been recognized with the Klachky Prize for advancing scientific frontiers and the 2015-16 Excelling Teacher award. His work bridges biophysics, virology, and drug design, with a focus on pathogen-related membrane proteins.

Lab Activities: The Arkin Lab investigates antiviral mechanisms and structural dynamics of transmembrane proteins using interdisciplinary approaches. Collaborations include molecular biology, computational modeling, and advanced spectroscopic techniques.