معرفی
Dr. Isabel K. Darcy is an Associate Professor in the Department of Mathematics at the University of Iowa, affiliated with the College of Liberal Arts and Sciences. She specializes in applying topological methods to biological problems, particularly focusing on DNA topology, protein-DNA interactions, and molecular biology. Her work bridges pure mathematics with computational and experimental biology, contributing to understanding knotting in proteins and DNA recombination processes.
She has organized workshops and conferences, such as the 2011 Topological Problems in Molecular Biology workshop, and collaborates with researchers globally. Her research has been supported by grants like the NSF VIGRE Grant #002242. Dr. Darcy teaches courses on differential equations, mathematical biology, and topology, and mentors undergraduate research projects in topological data analysis. Her lab develops software tools like TopoICE-X for visualizing topological outcomes of biochemical reactions.
Recent work includes modeling Mu transpososome structures and analyzing DNA recombination using tangle models. She actively participates in interdisciplinary initiatives through the Mathematical & Computational Biology group and the Applied Mathematical and Computational Sciences program at the University of Iowa.
