معرفی
Professor Isabel Bermudez-Diaz is a neuropharmacology researcher at the School of Biological and Medical Sciences, Oxford Brookes University. Her work focuses on ligand-gated ion channels, particularly nicotinic acetylcholine receptors (nAChR), with implications for diseases like Alzheimer’s, Parkinson’s, autism, and nicotine addiction.
Research spans structural-functional relationships of nAChR subtypes, allosteric modulation, and drug discovery using electrophysiology and mutagenesis in Xenopus oocytes. Recent publications address SARS-CoV-2 interactions with nicotinic receptors and flavonoid-based modulators.
- 2024: Protein interaction sites in Acetylcholine Binding Protein
- 2024: NS9283 analogues for (α4)3(β2)2 receptor modulation
- 2023: SARS-CoV-2 spike protein linkage to α7 nAChR
Scientific recognition includes awards from Leverhulme Trust and Brookes University Research Excellence. She supervises PhD students and contributes to BSc Biomedical Science and MSc Medical Genetics programs.
