Ian S. Haworth

Ian S. Haworth is an Associate Professor and Vice Chair of Pharmacology and Pharmaceutical Sciences at the USC School of Pharmacy, University of Southern California. He joined USC in 1992 after completing his PhD in Physical Organic Chemistry at the University of Liverpool and postdoctoral research at Oxford University. His laboratory develops computational algorithms to study molecular associations in nucleic acids, proteins, and drug-target interactions.

Education:

• PhD, University of Liverpool, UK (1986-1989)
• Postdoc, Oxford University, UK (1989-1992)
• BS, Manchester Metropolitan University

His research integrates computational chemistry, biology, and pharmaceutical sciences to understand molecular dynamics in biological systems. Key areas include nucleic acid structure prediction, aptamer design, transporter protein analysis, and MHC-peptide-TCR associations. This work emphasizes accurate modeling of biological interfaces for therapeutic development.

Haworth's recent publications focus on computational drug design (e.g., prodrug optimization, COX-2 inhibitors), structural biology (protein-nucleic acid complexes), and educational innovation (AI in pharmacy curriculum). His work consistently bridges computational predictions with experimental validation across therapeutic areas.

Research Grants:

• NIH/NIGMS R01GM059297: PEPT1 Structure-Function (2000-2006)
• NIH/NCI R29CA064299: Polyamine Antitumor Complexes (1994-2000)

He leads a computational lab developing tools like ALLNOX for biomolecular analysis and has contributed to transforming pharmacy education through case-based curricula. His team collaborates extensively across disciplines to study protein-membrane interactions, drug pharmacokinetics, and structural immunology.