Iain Buxton

Iain Buxton, a Professor of Pharmacology at the University of Nevada, Reno School of Medicine, has a distinguished career spanning pharmacology, cell signaling, and smooth muscle dynamics. His research focuses on uterine relaxation mechanisms in preterm labor and purinergic signaling in breast cancer progression.

• Pharm.D. from University of the Pacific
• Ph.D. in Biochemistry/Enzymology from North Carolina State University
• Postdoctoral work in Cardiovascular Pharmacology at UC San Diego
• Early research at Salk Institute under Nobel laureate Robert Holley

Research Interests center on preterm labor etiology, stretch-activated signaling in uterine smooth muscle, and tocolytic drug development. In cancer, he investigates exosomal NM23 signaling, purinergic mechanisms in angiogenesis, and metastasis.

Article Trends (2016-2025) reveal a focus on

• β3 adrenergic receptors in myometrial relaxation
• Connexin 43 phosphorylation and trafficking
• Piezo1 and TREK-1 channel modulation
• Exosomal NM23 in breast cancer metastasis
• S-nitrosoglutathione reductase (GSNOR) in labor dysregulation
• Pharmacological targeting of mechanosensitive pathways

Collaborative Networks include researchers like Dr. Sedaa Barnett, Dr. Shino Yokdang, and Dr. Haras Asif, with affiliations to institutions such as UC San Diego and Medipol University.