Hussam Al Kateb

Hussam Al Kateb, MSc, PhD is a board-certified Clinical Genomicist at Mayo Clinic in Rochester, Minnesota, holding dual certifications from the American Board of Medical Genetics and Genomics in Clinical Molecular Genetics and Clinical Cytogenetics. He specializes in developing and clinically implementing multi-omics testing strategies—including paired tumor-normal whole-exome, whole-transcriptome, and whole-genome analyses—to identify actionable, diagnostic, and prognostic variants in solid tumors.

Education & Training

• 2010 – Fellowship, Clinical Molecular Genetics, Case Western Reserve University & University Hospitals
• 2009 – Fellowship, Clinical Cytogenetics, Case Western Reserve University & University Hospitals
• 2007 – Post-doctoral Fellowship, Complex Disease Genetics (Type 1 Diabetes), University of Toronto & Hospital for Sick Children
• 2004 – PhD (Summa cum Laude), Human Molecular Genetics, Ruprecht-Karls-University of Heidelberg
• 1997 – MSc, Laboratory Diagnosis (Clinical Pathology), Damascus University
• 1992 – BSc, Pharmacy & Pharmaceutical Chemistry, Damascus University

Clinical & Research Focus

Dr. Al Kateb’s work bridges cutting-edge genomic technologies and precision oncology. His laboratory develops and validates next-generation sequencing (NGS) assays, interprets complex genomic data, and translates findings into clinical decision-making. Key areas include:

• Multi-omics test development for solid tumors
• Genotype-phenotype and genotype-outcome correlations in cancer
• Gene discovery and functional annotation of novel variants
• Optimization of NGS workflows and quality assurance

Scientific Awards & Honors

• Co-inventor, Patent WO2007131345 A1 (renal disease gene discovery in T1D)
• PhD Summa cum Laude, University of Heidelberg (2004)
• Young Investigator Award finalist, European Society of Human Genetics (2002)
• DAAD Scholarships for PhD and language studies (1999)
• Top graduate among 400, Damascus University College of Pharmacy (1992)

Professional Leadership & Memberships

Dr. Al Kateb serves on the Program Committee of the Cancer Genomics Consortium (2024–present), is a Certified Inspector for the College of American Pathologists, and maintains active memberships in the American College of Medical Genetics and Genomics (Fellow since 2012), American Society of Human Genetics, Association of Molecular Pathologists, and several editorial boards and guideline committees.

Laboratory & Collaborative Teams

He leads and collaborates with multidisciplinary teams at Mayo Clinic’s Department of Laboratory Medicine and Pathology, integrating genomic data with clinical pathology, oncology, and bioinformatics groups to advance precision cancer care and standardize genomic testing protocols worldwide.