معرفی
Huabo Su is a Professor at the Medical College of Georgia, Augusta University, with appointments in the Department of Pharmacology and Toxicology and the Vascular Biology Center. He leads an active research laboratory focused on protein modifications in cardiovascular biology and has received numerous prestigious awards including being named an APS-CV section fellow in 2022 and receiving an RO1 grant from NHLBI as Principal Investigator from 2019-2024.
Dr. Su's research focuses on understanding the biological function of ubiquitin-like protein modifiers including NEDD8 and Ufm1 in cardiomyocytes. His work aims to elucidate the molecular mechanisms of heart failure and identify novel therapeutic measures. He employs a range of approaches from in vitro molecular and cellular biology to proteomics and in vivo mouse physiology analyses.
- Cardiovascular Biology
- Protein Modifications (Neddylation, Ufmylation)
- Cardiac Development and Morphogenesis
- Mitochondrial Quality Control in the Heart
- Vascular Homeostasis
- Heart Failure Mechanisms
Dr. Su's recent publications demonstrate a strong focus on neddylation and its role in cardiac development, function, and disease. His work has revealed critical mechanisms by which protein modifications regulate cardiac physiology and has implications for understanding and treating heart failure.
Scientific Awards & Honors
- APS-CV section fellow, American Physiology Society Cardiovascular Section, 2022
- RO1, NHLB1, PI, 2019-2024
- AHA CDA (to Z.J.), Sponsor, 2019-2022
- AHA TPA, PI, 2019-2022
- AHA Postdoc Fellowship (to Z.J.), Sponsor, 2017-2019
- 2015 Outstanding Junior Faculty Award of the 2nd ACRE/APS symposium
- 2008 New Investigator Travel Award of the Basic Cardiovascular Sciences Conference
- Distinguished Faculty Award, Medical College of Georgia Faculty Senate, Augusta University, May 2025
- Distinguished Award of the Graduate School, Augusta University, April 2025
- Appointed chartered member, NIH MPPB Study Section, July 2024
Dr. Su actively mentors graduate students and postdoctoral fellows, with current advisees including Josue Zambrano-Carrasco (PhD student), Md Sadikul Islam, Yilang Li, and Jing Shi (postdoctoral fellows). He has successfully guided several students to completion of their degrees, including Rodney Littlejohn who defended his PhD thesis on "The Role of Neddylation in Early Cardiac Development" in June 2020. Dr. Su has secured significant research funding including NIH R01 grants and American Heart Association awards.
Dr. Su leads a vibrant research laboratory within the Vascular Biology Center at Augusta University. His lab investigates novel mechanisms underlying cardiomyopathy and heart failure, with particular emphasis on protein modifications mediated by small protein modifiers such as ubiquitin, NEDD8, and Ufm1.
