Hsuan An Chen

Hsuan An Chen is a Research Fellow at the Sloan Kettering Institute, affiliated with Memorial Sloan Kettering Cancer Center. His work focuses on cancer biology and immunology, particularly the interplay between epigenetic plasticity, tumor microenvironment dynamics, and immune surveillance mechanisms.

• Alumni of Gerstner Sloan Kettering Graduate School of Biomedical Sciences
• Active in multidisciplinary cancer research spanning pancreatic, gastric, and prostate malignancies

Research interests center on:

• Epigenetic regulation in tumorigenesis
• Senescence and immune microenvironment interactions
• Genotype-specific metastatic mechanisms
• Cell-cell communication in cancer progression

Recent publications highlight his contributions to understanding how epigenetic plasticity drives pancreatic cancer development (2023) and genotype-specific metastasis in gastric cancer (2024). His work frequently utilizes mouse models and integrates molecular biology with immunologic perspectives.

• Collaborator on studies across Cancer Discovery, Nature Cancer, and Science
• ORCID: 0000-0002-8979-3670