Hongyu An

Hongyu An is a Professor of Radiology and Professor of Neurology at Washington University in St. Louis, affiliated with the Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS), the Institute of Clinical and Translational Sciences (ICTS), and the Siteman Cancer Center. They lead research in the Division of Radiological Sciences with a focus on developing novel imaging methods to improve clinical diagnosis and patient management.

Dr. An's research centers on MR imaging and combined PET/MR imaging with expertise in MRI physics, sequence design, image reconstruction, and deep learning applications. Their work spans MR oxygen metabolic imaging, perfusion imaging, susceptibility-weighted imaging, diffusion MR imaging, and quantitative measurements. The research has significant applications in cerebral small vessel disease and sickle cell disease, with innovations in attenuation correction techniques and motion-compensated MRI.

With 154 total research outputs and 5,646 citations, Dr. An has maintained a robust publication record from 1999 to 2025, with increasing output in recent years (12 publications in 2023, 12 in 2024, and at least 7 in 2025). Their work shows strong trends in applying deep learning to medical imaging challenges, particularly in reconstruction algorithms, attenuation correction, and disease-specific applications.

• Research fingerprint shows 100% concentration in Magnetic Resonance Imaging
• Significant connections to Oxygen Extraction Fraction (75%), PET-MRI (66%), and Sickle Cell Disease (51%)
• Work has been mentioned in 21 news outlets and shared across multiple social media platforms

Dr. An is available to mentor PhD/MSTP students and has developed several novel techniques including deep learning-based MR-derived pseudo-CT for PET/MR attenuation correction and motion-compensated dynamic contrast-enhanced MRI in the liver, demonstrating practical applications that reduce radiation exposure and improve patient comfort.