Holly C Boyer

Holly C Boyer is an Associate Professor in the Department of Otolaryngology at the University of Minnesota. Her research focuses on disorders of the upper airways, particularly in patients with cystic fibrosis and hereditary hemorrhagic telangiectasia.

Her primary research interests include:

• Cystic Fibrosis and upper airway complications
• Chronic Rhinosinusitis and microbiome interactions
• Hereditary Hemorrhagic Telangiectasia and epistaxis management
• Sclerotherapy techniques for vascular disorders
• Microbial ecology of the upper respiratory tract
• Pathological bone formation in sinus disorders

Dr. Boyer's recent publications demonstrate a strong focus on the microbiological aspects of cystic fibrosis sinus disease, with particular attention to how microbial communities differ between upper and lower airways. Her work employs advanced techniques like 16S rRNA gene sequencing to characterize microbial signatures. She has also investigated risk factors for pathological bone formation in chronic sinusitis and developed innovative approaches to manage bleeding in hereditary hemorrhagic telangiectasia.

Her current research projects include:

• Pomalidomide for the Treatment of Bleeding in Hereditary Hemorrhagic Telangiectasia (2021-2024)
• The efficacy of Cayston in disrupting bacterial nutrition (2015-2018, as Co-Investigator)
• Pulmonary aspiration of sinus secretions in patients with cystic fibrosis (2013-2015)
• Office-sclerotherapy for epistaxis due to hereditary hemorrhagic telangiectasia (2011-2014)

Dr. Boyer has received funding from significant sources including the NIH National Heart, Lung and Blood Institute, Cleveland Clinic, Gilead Sciences, Inc., and the American Academy of Otolaryngology. Her work contributes to Sustainable Development Goals related to good health and well-being, particularly in improving care for patients with chronic respiratory conditions.