Ho-Joon Lee

Ho-Joon Lee is a Research Scientist in Genetics at Yale University's School of Medicine. He holds a PhD in Computational Biology from the Free University of Berlin and has conducted postdoctoral research at Harvard University and the Max Planck Institute. His work focuses on integrating artificial intelligence (AI), machine learning (ML), and systems biology to address complex biological and medical questions.

Research Interests:

• AI/ML applications for stroke etiology classification and drug discovery
• Multi-omics data analysis (single-cell, proteomic, metabolomic)
• Network medicine and metabolic pathway modeling
• Cancer metabolism and immunology

Key Projects:

• Developed StrokeClassifier for ischemic stroke diagnosis using EHR and MRI data (2 patents pending)
• Meta-modeling for ligand-protein binding affinity prediction
• Systems biology analysis of West Nile virus infection and pancreatic cancer

Education:

• PhD, Free University of Berlin, Computational Biology (2008)
• MSc, Swansea University, Quantum Fields and Symmetry (1999)
• BSc, Yonsei University, Physics (1997)

Grants & Collaborations:

Recipient of a seed grant from the Northeast Big Data Innovation Hub. Collaborates with labs at Yale, Harvard, and the University of Michigan on interdisciplinary projects.

Labs/Teams:

• Gerstein Lab (Yale)
• Lyssiotis Lab (University of Michigan)
• Spiegel Lab (Yale)