معرفی
Hing Y Leung is Professor of Urology and Surgical Oncology (Clinical Research Garscube) and Director of Innovation, Engagement and Enterprise at the School of Cancer Sciences, University of Glasgow. Based at the Beatson Institute, his laboratory investigates molecular mechanisms of prostate cancer progression, focusing on FGF receptor and ERK5 signaling pathways. His work integrates in vitro and in vivo models to develop prognostic biomarkers and therapeutic strategies.
Research Focus: His team explores aberrant signaling in prostate carcinogenesis, with emphasis on lipid metabolism (e.g., SREBP pathways), tumor microenvironment interactions, and resistance mechanisms in castration-resistant prostate cancer (CRPC). Collaborative projects bridge basic science with clinical translation, including diagnostic innovations like biosensors for urinary biomarkers and imaging techniques.
Publication Trends: Recent articles (2021-2025) demonstrate a multidisciplinary approach spanning molecular oncology (e.g., ARID1A, MBTPS2), surgical outcomes (RALP centralization), metabolic reprogramming, and novel diagnostics. Key themes include therapeutic targeting of signaling networks, biomarker validation, and clinical trial design for advanced prostate cancer.
Leadership & Infrastructure: As Director of Innovation, he oversees translational research infrastructure, including biorespositories. He leads the Urology Research Group and collaborates extensively with NHS Glasgow, leveraging clinical samples for mechanistic studies.
