Helle Krogh Johansen

Helle Krogh Johansen serves as Clinical Professor at the University of Copenhagen's Faculty of Health and Medical Sciences within the Department of Clinical Medicine, specializing in Clinical Microbiology at Blegdamsvej 3, Copenhagen. Her dual institutional affiliation bridges academic research at KU with clinical practice at the Capital Region of Denmark (Region H), evidenced by her regionh.dk email and active research profile.

Her research focuses on clinical microbiology with emphasis on cystic fibrosis pathogen dynamics, antimicrobial resistance mechanisms, and genomic epidemiology of bacterial infections. Key investigations include Pseudomonas aeruginosa evolution in chronic lung disease, vancomycin-resistant Enterococcus transmission patterns, and development of tissue-on-a-chip infection models. Recent work analyzes CFTR modulator impacts on pulmonary pathogens and respiratory virus roles in pediatric cystic fibrosis.

Analysis of her 2025 publications reveals dominant trends in longitudinal cohort studies (Danish cystic fibrosis registry), advanced genomic techniques (whole-genome sequencing of resistant pathogens), and translational models for bacterial infection imaging. Her work consistently addresses clinical microbiology challenges through interdisciplinary collaboration spanning bacteriology, pulmonology, and molecular genetics.

Dr. Johansen actively collaborates with the TransformCF Study Group and Danish cystic fibrosis centers, contributing to national surveillance of respiratory pathogens. Her laboratory work integrates clinical microbiology with cutting-edge tissue engineering approaches for live bacterial infection analysis, particularly focusing on Pseudomonas aeruginosa persistence mechanisms in cystic fibrosis airways.