معرفی
Hege Christensen is a Professor of Pharmacology at the University of Oslo's Department of Pharmaceutical Biosciences. She has been affiliated with the Department since 1992 and holds leadership roles in academic programs such as the Master's Degree in Pharmacy and Clinical Pharmacy. Her research focuses on pharmacokinetics, particularly drug metabolism variability due to genetic and environmental factors, and drug interactions. She collaborates with institutions like the IMUP Center for Immunopharmacology in Transplantation and the School of Pharmacy at the University of Manchester. Key areas include physiology-based pharmacokinetic modeling and in vitro-in vivo extrapolation techniques.
Christensen's education includes a Cand.pharm. from the University of Oslo (1986), a Dr.scient. (1992), and an Advanced Diploma in Clinical Pharmacy Teaching from the University of Leeds (1996). Her career spans roles at the International Heart Research Institute (1991–1992) and pharmaceutical industries like Løvens Kemiske Fabrik (1986–1987).
Her research interests emphasize understanding drug bioavailability and optimizing therapies through pharmacokinetic studies. Recent work investigates gastric bypass surgery's effects on drug metabolism and the role of microbiome signatures in weight loss outcomes. She has published extensively in journals like Clinical Pharmacokinetics and Mucosal Immunology, with a focus on cytochrome P450 enzymes, drug transporters, and obesity-related pharmacology.
Notable collaborations include projects with Professor Amin Rostami-Hodjegan at the University of Manchester, exploring advanced pharmacokinetic modeling. Her work bridges clinical and translational research, addressing challenges in drug dosing for patients with obesity and comorbidities.
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