Harlan Linver Pietz

Harlan Linver Pietz, MD, PhD, is a researcher at the Yale School of Medicine, Yale University. His work focuses on virology, immunology, and pharmacology with an emphasis on vaccine development, infectious disease mechanisms, and drug discovery. He holds a BS from the University of Washington (2014), an MD from Weill Cornell Medicine (2024), and a PhD in Biomedical Sciences from The Rockefeller University (2022).

Research Interests: Dr. Pietz’s research spans herpes simplex virus (HSV) vaccine development, SARS-CoV-2 pathogenesis in pregnancy, multidrug resistance mechanisms, and structural biology of transport proteins. He has contributed to studies on HIV treatment resistance and CFTR channel modulation. His work integrates clinical trials, molecular biology, and computational modeling to address translational challenges in infectious diseases.

Publications Trends: Recent work highlights structural insights into drug resistance proteins (2025), immune responses to HSV vaccines across sexes (2023), and viral load dynamics in pregnant populations during SARS-CoV-2 infection (2024). These studies bridge basic science and clinical applications, particularly in vaccine design and precision medicine.

• Notable collaborations include work with John S. Tsang (structural biology) and Jason I. Cohen (vaccine trials).
• Focus areas: Antiviral drug discovery, innate immunity modulation, and translational virology.

Labs/Teams: Engaged in interdisciplinary teams at Yale’s Department of Immunology and the Stephen & Denise Adams Center for Parkinson’s Disease Research through systems immunology initiatives.