معرفی
Associate Professor Hao-Wen Sim is a Medical Oncologist and Clinical Lead at Chris O'Brien Lifehouse and The Kinghorn Cancer Centre, affiliated with the University of Sydney. He holds a MBBS(Hons) with Biostatistics training, and is a Fellow of the Royal Australasian College of Physicians. His research focuses on neuro-oncology clinical trials, particularly investigator-initiated brain cancer trials through his leadership roles in COGNO (Cooperative Trials Group for Neuro-Oncology).
Education includes an MBBS(Hons) from The University of Melbourne and a Master of Biostatistics from The University of Sydney, where he received multiple awards including the Biostatistics Collaboration of Australia Star Graduate Award. He completed a neuro-oncology fellowship at The Princess Margaret Cancer Centre in Toronto.
Research interests center on brain tumor treatment optimization, trial methodology, biomarker development (e.g., extracellular vesicle-based diagnostics), and improving clinical trial accessibility. He leads major initiatives like the NUTMEG immunotherapy trial for glioblastoma and the MAGMA multi-arm glioma trial platform.
Key awards include Les Irwig Award in Epidemiology and Australasian Epidemiological Association prizes. His clinical work combines treating brain cancer patients with advancing trial designs addressing barriers like travel distance impacts (as shown in Internal Medicine Journal 2023).
Grants include MRFF funding for Australian Brain Cancer Research Infrastructure and Rare Disease initiatives. He chairs COGNO's International Clinical Research Subcommittee and contributes to global neuro-oncology collaboration strategies.
Labs/Teams: Active in COGNO, NHMRC Clinical Trials Centre, and the Australian Brain Cancer Mission initiatives. Leads the MAGMA and LUMOS trials focusing on molecularly guided therapies for gliomas.
