Hans-Uwe Simon

Hans-Uwe Simon is a Professor of Pharmacology at the Faculty of Medicine, University of Bern, Switzerland, and serves as Deputy Director of the Institute of Pharmacology there. He also holds current roles as President of Brandenburg Medical School (Germany), Full Professor at Sechenov University's Department of Clinical Immunology and Allergology (Russia), and Principal Investigator at Kazan Federal University's Institute of Fundamental Medicine and Biology (Russia).

• MD, University of Jena (1986)
• Dr. med., University of Jena (1986)
• Habilitation in Experimental Immunology, University of Zurich (1996)
• PhD in Pharmacology, Hebrew University of Jerusalem (2001)

Simon's research focuses on cell death mechanisms (apoptosis, necroptosis, mitotic catastrophe), autophagy, and their roles in inflammatory diseases and cancer biology. He investigates granulocyte biology (eosinophils, neutrophils), extracellular trap formation, and hypereosinophilic syndromes, including the development of targeted therapies like mepolizumab.

His most recent articles (2017-2021) explore autophagy in eosinophil function, energy requirements for extracellular traps, and necroptosis conditions. Earlier work (1996-2010) established foundational knowledge in eosinophil survival, hypereosinophilic syndrome classification, and clinical drug development.

Scientific Recognition

• Paul Martini Prize (1997)
• Georg Friedrich Götz Prize (2000)
• Pfizer Research Prize (2003)
• Phoenix Science Prize (2020)
• Doctor honoris causa, University of Ljubljana (2017)
• Doctor honoris causa, South Ural State Medical University (2021)

Simon has served as Editor-in-Chief of Allergy, Int. Arch. Allergy Immunol., and Cell Death & Disease. He has led academic societies including the Swiss Society of Pharmacology and Toxicology (SSPT) and European Cell Death Society (ECDO).