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معرفی
Hanna Chan is a Researcher in Molecular Immunology at the Faculty of Medicine, University of Oslo, Norway (2024-present), previously serving as a Doctoral Research Fellow at the same institution (2018-2024). Her work focuses on T-cell biology and intracellular signaling mechanisms within immune responses.
Her educational background includes:
- MSc in Immunology, Imperial College London (2017-2018), thesis: "The Role of DYRK1A in B Cell Survival" at The Francis Crick Institute
- BSc in Biological Sciences, Nanyang Technological University, Singapore (2012-2016), thesis: "Impact of Cutaneous Dendritic Cell Subsets on the Evolution of Lymphoid Cells in Response to Propionibacterium acnes" at Singapore Immunology Network
Dr. Chan's research centers on Immunology, Intracellular signalling, and T cell biology and function, with specific focus on molecular mechanisms of T-cell activation. She investigates how adaptor proteins and kinases (particularly Src/Tec-family) regulate immune signaling pathways, aiming to elucidate their roles in autoimmune disease development through studies of protein interactions and kinase regulation.
Her recent publications (2019-2024) demonstrate a cohesive research trajectory in T-cell signaling, featuring methodological innovations like CRISPR/Cas9 gene editing in Jurkat T cells and mechanistic studies of adapter proteins (e.g., TSAd) and kinase regulation. This work bridges molecular immunology and cell signaling, emphasizing adapter protein dynamics and kinase activity control in immune responses.
No scientific awards were mentioned in the provided text.
No information regarding student advising or research grants was provided in the source material.
She is an active member of the "T Cell Activation and Autoimmune Disease" research group at the University of Oslo, contributing to investigations of molecular pathways underlying immune dysregulation.
