Hajo Kries

Prof. Dr. Hajo Kries is a Professor at the Institute of Biochemistry and Technical Biochemistry, University of Stuttgart, specializing in Technical Biochemistry. His research focuses on enzyme engineering, natural product biosynthesis, and synthetic biology approaches to design novel biocatalysts.

Key research areas include reprogramming nonribosomal peptide synthetases, elucidating biosynthetic pathways of complex natural products, and developing high-throughput screening methods for enzyme engineering. His work bridges chemical biology, enzymology, and metabolic engineering.

Recent publications demonstrate innovations in directed evolution of megasynthetases, mechanistic studies of cyclopropanol formation in natural products, and the engineering of noncanonical amino acid incorporation. Research consistently addresses fundamental questions in enzyme specificity while developing tools for therapeutic peptide production.