معرفی
H. Josh Jang is an Assistant Professor in the Department of Cell Biology at Van Andel Institute, where he leads the Jang Laboratory focused on improving cancer immunotherapies through epigenetic and metabolic research. He joined the Institute in 2025 after serving as a VAI Fellow (2020-2025) under Nobel laureates Peter A. Jones and Stephen B. Baylin.
- Education: B.S. in Health Promotion and Disease Prevention (University of Southern California), Ph.D. in Molecular Genetics and Genomics (Washington University in St. Louis)
- Key Collaborations: Van Andel Institute–Stand Up To Cancer® Epigenetics Dream Team
His research explores the epigenetic-metabolic crosstalk in cancer progression, targeting reversible vulnerabilities to enhance immune checkpoint inhibitors. Current projects include transposable element activation, RNA splicing dysregulation, and tumor microenvironment characterization using single-cell and spatial sequencing technologies.
Recent publications demonstrate expertise in multi-omics analysis, clinical trial design, and epigenetic therapy optimization across diverse cancers. His work has generated 15 clinical trials through the VAI-SU2C Dream Team collaboration.
- Scientific Awards:
- K99/R00 Pathway to Independence grant (NCI)
- SPORE Epigenetic Therapies Career Enhancement Award (NCI)
- Forbeck Scholar (2021)
