معرفی
Guus van Zadelhoff is a Researcher and Education Officer at the Faculty of Science, Utrecht University, specializing in Cellular Protein Chemistry. Since 2008, he has focused on protein folding in mammalian endoplasmic reticulum, chaperone characterization, and radiation safety. Previously, he studied fatty acid oxidation (1996–2008) and glycoprotein analysis (1990–1996) at Utrecht University.
Research interests span protein folding mechanisms, lipoxygenase enzyme systems, oxylipin metabolism, and endocannabinoid signaling. His work integrates
- Cell culture and radiological labeling
- Chromatographic methods (FPLC, HPLC)
- Spectroscopic and polarographic assays
- Structural analysis of protein fragments
Publications highlight trends in
- Lipoxygenase substrate specificity (2000–2023)
- Endocannabinoid oxygenation (2010–2023)
- Protein folding checkpoints in HIV (2015–2021)
- Stress granule formation in Drosophila (2015)
- Photoprotectant-oxylipin interactions (2013)
Collaborations include researchers like Marc Maccarrone, Isaac Braakman, and Mauro Maccarrone, with contributions to journals such as Cell Reports, Journal of Biological Chemistry, and European Journal of Biochemistry. He provides practical training to undergraduate students and employs techniques like immunoprecipitation, SDS-PAGE, and LC-MS.
