Guohao Dai

Guohao Dai is a Professor of Bioengineering at Northeastern University, located at 360 Huntington Ave, Boston, MA. His research focuses on 3-D bioprinting, stem cell technology, and vascular bioengineering. He leads the Guohao Dai Lab, which investigates vascular regeneration and disease mechanisms, developing novel therapies for vascular-related disorders. Dai has held positions at Harvard Medical School (post-doc) and MIT (Ph.D. in Biomedical Engineering), with earlier degrees from Peking University.

Education

• Post-doctoral Research, Vascular Biology, Harvard Medical School
• Ph.D., Biomedical Engineering, Massachusetts Institute of Technology
• M.S., Biomechanics, Peking University
• B.S., Mechanical Engineering, Peking University

Research Interests

Dai’s work integrates bioengineering approaches with stem cells and vascular biology to address challenges in tissue regeneration and vascular diseases. Key areas include:

• 3D bioprinting of functional vascular networks
• Stem cell differentiation in vascular niches
• Neurovascular interactions in brain disorders
• Biomaterial design for regenerative medicine

Recent Research Highlights

Recent studies focus on engineering 3D brain-vascular models for glioblastoma research, developing biodegradable hydrogels for bioprinting, and understanding transcriptional regulation of vascular differentiation. His work bridges mechanobiology with clinical applications, such as islet transplantation and skin graft engineering.

Awards & Recognition

• 2014 NSF Career Award
• 2023 AIMBE Fellow
• 2024 BMES Fellow
• 2023-2025 BMES Board of Directors
• Consistently ranked in Stanford’s Top 2% Most-Cited Scientists (2020–2024)

Advising & Grants

Dai oversees multiple grants, including NASA and NIH funding, and mentors students in the PEAK Experiences program. He has patented biodegradable hydrogels for bioprinting and co-leads interdisciplinary initiatives at Northeastern’s Institute for Mechanobiology.

Labs & Collaborations

His lab collaborates with the Institute for Mechanobiology and the Biomedical Engineering Society. Research projects include vascular niche engineering, 3D tumor models, and regenerative therapies.