Guilherme Indig

Guilherme Indig is a Professor Emeritus in the Department of Chemistry & Biochemistry at the University of Wisconsin-Milwaukee (UWM), within the College of Letters & Science. His research focuses on photochemistry and photobiology, particularly the development of tumor imaging and therapy techniques using fluorescent and phototoxic agents. He holds a PhD from the University of São Paulo, Brazil.

Education:

• PhD in Chemistry, University of São Paulo, Brazil

Research Interests:

Indig’s work bridges chemistry and biology, emphasizing mitochondrial targeting and receptor-assisted tumor targeting. His studies investigate how cationic dyes accumulate in tumor cell mitochondria due to enhanced mitochondrial membrane potential, aiming to optimize selective phototoxicity. He also explores fluorescence-guided tumor margin delineation during surgery and ‘see-and-treat’ approaches using receptor-targeted agents (e.g., folate, VEGF receptors). Techniques include physical-organic photochemistry, biophysics, and cell biology.

Publications:

Indig has authored over 15 papers, with recent work on polymeric micelles for apoptosis-targeted imaging (2014), mitochondrial targeting models (2011), and photophysical properties of dyes (2005–2000). His research underscores the interplay between molecular structure, cellular localization, and therapeutic efficacy in photodynamic therapy.

Grants & Advising:

No specific grants or advisees are listed in the provided text. His contributions focus on foundational research rather than direct student supervision.

Labs/Teams:

No specific lab affiliations or collaborative teams are explicitly mentioned.