Guido Nolte

Dr. Guido Nolte is the Head of the Working Group at the Institute of Neurophysiology and Pathophysiology, part of the Center for Experimental Medicine at the University Medical Center Hamburg-Eppendorf (UKE). He specializes in neurophysiological research with a focus on electrophysiological signal analysis, brain connectivity, and neural oscillations. His work integrates advanced EEG/MEG techniques to study cortical networks and their interactions in both healthy individuals and clinical populations.

Dr. Nolte holds a doctoral degree (Dr. rer. nat) in natural sciences and has extensive experience in developing novel methods for analyzing neural signals, including bispectral analysis, spatial filtering, and source localization. His research interests span cross-frequency coupling, phase-amplitude interactions, and the application of signal processing techniques to understand cognitive and clinical phenomena.

Key research areas include studying how brain connectivity patterns predict behavioral outcomes in multisensory tasks, optimizing spatial filtering for improved source localization, and investigating the effects of neuromodulation techniques like transcranial alternating current stimulation (tACS). He also explores neural mechanisms underlying speech comprehension and emotion regulation disorders such as borderline personality disorder.

His recent publications emphasize methodological advancements in EEG/MEG data analysis, including robust estimation of time delays under noise, causal inference in cortical networks, and the development of tools like Source-to-Sensor Coupling (SoSeC) for source localization. His work contributes to both basic neuroscience and clinical applications in neurological and psychiatric conditions.