معرفی
Dr. Gregory Tietjen is an Adjunct Professor in the Department of Surgery at Yale School of Medicine, specializing in transplantation and immunology. He holds a PhD in Biophysics from the University of Chicago and a BS in Physics from the University of Oregon, complemented by a BA in English from Wake Forest University. His research focuses on integrating molecular biophysics and biomedical engineering to develop precision therapies using non-transplanted human organs. Key areas include ex vivo organ perfusion systems for kidney assessment, targeted nanomedicine delivery to vascular endothelium, and overcoming microvascular obstructions in preserved organs.
Notable achievements include the 2022 Basic Science Career Development Award from the American Society of Transplantation. His work bridges clinical translation with advanced imaging (e.g., contrast-enhanced CT for kidney evaluation) and nanotechnology, emphasizing ex vivo platforms for therapeutic testing. Collaborations with institutions like the University of Cambridge advance vascular-targeted nanoparticle applications during organ perfusion. Ongoing projects explore real-time 3D nanoparticle tracking and molecularly targeted nanomedicines to enhance graft viability and reduce allograft rejection risks.
- Education:
- PhD, Biophysics, University of Chicago (2013)
- BS, Physics, University of Oregon (2008)
- BA, English, Wake Forest University (2002)
- Key Research Themes:
- Ex vivo organ preservation and revitalization
- Endothelial-targeted drug delivery systems
- Mechanisms of cold-storage injury in kidneys
- Immunomodulation in transplantation
- Labs/Teams: Tietjen Lab (Yale School of Medicine)
