معرفی
Gregory J. Pazour is a Professor at the Program in Molecular Medicine, UMass Chan Medical School, with affiliations at T.H. Chan School of Medicine and Morningside Graduate School of Biomedical Sciences. He holds roles in the Interdisciplinary Graduate Program, MD/PhD Program, and Postbaccalaureate Research Education Program. His research focuses on cilia biology, their assembly, and roles in health and disease, particularly in kidney development and congenital heart defects.
Education: B.A./B.S. in Chemistry & Biology (South Dakota State University, 1986), Ph.D. in Biochemistry (University of Minnesota, 1991). Postdoctoral work at Worcester Foundation for Biomedical Research.
Research Interests: Ciliary dysfunction links to structural birth defects, kidney diseases (e.g., polycystic kidney disease), heart malformations, and sensory disorders. Key projects include investigating cilia assembly mechanisms, Hedgehog signaling, and cilia’s role in organ patterning.
Recent publications emphasize ciliary proteins’ roles in disease (e.g., TMEM67, IFT140), signaling pathways (Hedgehog, Wnt), and genetic causes of ciliopathies. Awards include the American Society for Cell Biology Fellowship and the Lilian Jean Kaplan Prize.
Grants and advising: Active in mentoring students and postdocs in cilia research. Labs: Pazour Lab explores cilia’s functional and structural roles in health and disease.
