Graeme Sills

Dr. Graeme Sills is a Senior Lecturer in Pharmacology and Director of Education (Cardiovascular & Metabolic Health) at the University of Glasgow’s School of Life Sciences. His contact details include the email Graeme.Sills@glasgow.ac.uk and a telephone number (0141 330 4140). He graduated with a first-class honours degree in Pharmacology from the University of Glasgow in 1990 and earned his PhD in 1994, focusing on experimental seizure models and antiepileptic drugs.

His research interests center on epilepsy drug mechanisms, clinical neuropharmacology, and drug resistance. Areas of exploration include blood-brain barrier transporters, genomics, inflammation, and oxidative stress in epilepsy. He has pioneered the use of non-mammalian species (e.g., Caenorhabditis elegans) for antiseizure drug discovery, as seen in collaborative studies like the SANAD II trials. His work bridges preclinical and clinical research, emphasizing personalized medicine and therapeutic innovation.

Dr. Sills has contributed to over 140 publications, including landmark studies on genetic predictors of drug resistance and biomarker identification. He collaborates with international consortia (e.g., Epi25, EuroEPINOMICS-CoGIE) and has authored book chapters on antiepileptic drug mechanisms and clinical trial methodologies. His research often integrates genetic, proteomic, and neurochemical approaches to understand epilepsy’s complex etiologies and improve treatment strategies.

In education, he leads programs in cardiovascular and metabolic health, focusing on translating pharmacological research into teaching. His interdisciplinary work spans neuroscience, clinical pharmacology, and statistical analysis to address gaps in epilepsy drug development and patient outcomes.