معرفی
Graeme Mardon, Ph.D. is the James R. Davis Chair in Pathology and Immunology and a Professor in the Departments of Molecular and Human Genetics, Neuroscience, Ophthalmology, and the Programs in Developmental Biology and Integrative Molecular and Biomedical Sciences at Baylor College of Medicine in Houston, Texas. He also serves as Co-Director of the Graduate Program in Molecular and Human Genetics.
Education
- BS, Haverford College (1980)
- PhD, Massachusetts Institute of Technology (1990)
- Postdoctoral Fellowship, University of California, Berkeley (1994)
Research Focus
Dr. Mardon's laboratory investigates the molecular mechanisms of retinal development using both Drosophila melanogaster and mouse models. The overarching goal is to translate insights into improved diagnosis, prevention, and treatment of human retinal diseases. Key areas include:
- Retinal cell fate determination and differentiation
- Epidermal Growth Factor Receptor (EGFR) signaling in retinogenesis
- Functional genomics of eye development genes (eyeless, eyes absent, sine oculis, dachshund)
- Gene therapy for Leber congenital amaurosis and retinitis pigmentosa
- Single-cell RNA-seq and ATAC-seq to map gene-regulatory networks
Scientific Awards
- Best Lecturer, 8-Stranded Beta-Barrel Jelly Roll Awards, Baylor College of Medicine (2008)
- James M. Barr Award for Outstanding Retina Research Achievement (2006, 2002)
- Marc Dresden Excellence in Graduate Education Award, Baylor College of Medicine (2001)
- Brochstein Award for Outstanding Achievement in Retina Research (1999)
Advising & Grants
As Co-Director of the Graduate Program in Molecular and Human Genetics, Dr. Mardon mentors and advises numerous Ph.D. students and postdoctoral researchers. His laboratory has received continuous funding from the NIH and other agencies to support projects spanning basic developmental biology to translational gene-therapy trials.
Laboratory & Affiliations
The Mardon Lab is housed within the Departments of Pathology & Immunology and Molecular and Human Genetics at Baylor College of Medicine. The lab integrates genetics, genomics, computational biology, and advanced imaging to dissect conserved pathways governing eye formation and function in both flies and mice.
