Grace W. Pien

Grace W. Pien, M.D., M.S.C.E., is an Associate Professor of Medicine in the Division of Sleep Medicine at the Perelman School of Medicine, University of Pennsylvania. She serves as an Attending Physician at the Hospital of the University of Pennsylvania and a Staff Physician at the Corporal Michael J. Crescenz VA Medical Center.

• A.B. in Biology, Harvard University (1990)
• M.D., Columbia University College of Physicians and Surgeons (1994)
• M.S.C.E., Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine (2004)

Dr. Pien specializes in sleep disorders affecting women, particularly sleep-disordered breathing during pregnancy and its impact on maternal-fetal health. Her ongoing research includes a longitudinal study on postmenopausal women's increased risk for obstructive sleep apnea, focusing on hormonal and physiological mechanisms.

Her recent publications (2021-2025) emphasize maternal sleep patterns, fetal heart rate responses, and longitudinal analysis of obstructive sleep apnea subtypes. These works span sleep epidemiology, obstetric complications, and clinical guideline development.

• NIH Research Project Grant
• NIH Mentored Patient-Oriented Research Career Development Award
• American Heart Association Scientist Development Award

Dr. Pien is affiliated with the Division of Sleep Medicine at the University of Pennsylvania, collaborating on multidisciplinary studies with the Department of Medicine and VA Medical Center. Her work integrates clinical practice, epidemiological research, and translational medicine.