معرفی
Glennis Logsdon, Ph.D., is an Assistant Professor of Genetics at the University of Pennsylvania and a Core Member of the Penn Epigenetics Institute. She leads the Logsdon Lab, focusing on centromere biology, human genome completion, and synthetic chromosome engineering. Her work has resolved centromeres, previously missing from the human genome, enabling studies on their genetic and epigenetic variation in health and disease.
Education:
- B.A. in Biochemistry, University of Pennsylvania (2011)
- Ph.D. in Biochemistry and Molecular Biophysics, University of Pennsylvania (2018)
Her research leverages long-read sequencing and synthetic biology to:
- Determine centromere variation in human populations using data from the Human Pangenome Reference Consortium
- Reconstruct centromere evolution over 25 million years via the Telomere-to-Telomere Consortium
- Engineer human artificial chromosomes (HACs) with novel centromeres for medical applications
Her 15 most recent articles (2025-2023) span genomic variation, primate evolution, and HAC design, with methodologies in long-read sequencing, phylogenetics, and computational assembly. Notable collaborations include the Human Genome Structural Variation Consortium and Project 8p.
Scientific Awards:
- Featured on Science Friday (2025) for genome research impact
She mentors Ph.D. students in Genomics and Computational Biology, advising projects on centromere epigenetics, 3D chromatin architecture, and African pangenome construction. Her lab also includes postdoctoral fellows and bioinformatics specialists, with grants supporting centromere variation and synthetic biology initiatives.
