معرفی
Giovanna Poce serves as Associate Professor of Medicinal Chemistry at Sapienza University of Rome's Department of Chemistry and Pharmacy Technology within the Faculty of Pharmacy and Medicine. She coordinates the PhD course in Molecular Design and Characterization for Health Promotion and serves as Associate Editor for Frontiers in Chemistry.
- Ph.D. in Medicinal Chemistry, Sapienza University of Rome (2008)
- Master’s Degree in Pharmaceutical Chemistry and Technology, Sapienza University of Rome (2004)
Her research focuses on designing small molecules against infectious diseases, particularly tuberculosis and malaria transmission-blocking agents. Utilizing structure-based drug design, protein crystallography, and molecular docking, her lab targets novel pathways like MmpL3 inhibition for TB and Plasmodium lifecycle interruption for malaria eradication. Recent work expands into antiviral compounds against enteroviruses.
Analysis of her 15 most recent publications reveals dominant themes in tuberculosis drug discovery (40%), malaria transmission-blocking strategies (20%), and antiviral research (25%), with strong emphasis on structure-activity relationships and nano-delivery systems. Her work frequently addresses drug resistance mechanisms through novel target identification.
As Principal Investigator, she leads grants totaling €182,287 including projects on pyrazole derivatives for tuberculosis and tri-anthranilates as antitubercular agents. She collaborates internationally with Harvard, University of Cape Town, and University of Pretoria researchers. Her MEDCHEMLAB (Room 204, CU019 Building) operates at 100% research capacity with advanced chemical synthesis and analysis equipment for drug development.
