معرفی
Geraldine Mitchell is a Clinical Associate Professor in the School of Nursing, Midwifery and Paramedicine, Faculty of Health Sciences. Her research focuses on advancing regenerative medicine through tissue engineering and vascular biology, particularly in liver bioengineering, endothelial cell function, and the development of functional vascular networks. She employs interdisciplinary approaches involving stem cells, biomaterials, and in vivo models to address challenges in organoid differentiation, fat graft survival, and adipose-derived progenitor cell potential.
Her work explores the role of endothelial cells in modulating organoid development and leverages innovative methods like vascularized bioreactors and porous scaffolds to enhance tissue viability. Key contributions include studies on nitric oxide signaling in stem cell differentiation, epigenetic profiling of adipose-derived progenitors, and the application of microRNAs to understand metabolic disorders.
Research interests span liver niche recapitulation, angiogenesis regulation via PI(4,5)P2 pathways, and the integration of biocompatible materials for 3D scaffold vascularization. Collaborations with multidisciplinary teams emphasize translational applications in regenerative medicine and biomedical engineering.
