معرفی
Georgia Charkoftaki is an Associate Research Scientist in the Department of Environmental Health Sciences at Yale School of Public Health. She is affiliated with the Vasiliou Lab and the Yale Superfund Research Center, where she conducts research at the intersection of metabolomics, lipidomics, and neurodevelopmental disorders.
Dr. Charkoftaki received her pharmacy degree, MSc in drug delivery, and PhD in biopharmaceutics-pharmacokinetics from the University of Athens, Greece. She completed a postdoctoral fellowship in clinical and translational science at UC Denver, focusing on kidney-related diseases and the pharmacokinetics of cyclophosphamide in dialysis patients.
Her research focuses on bile acids as neuromodulators in alcoholism and neurodevelopmental disorders, and the role of aldehyde dehydrogenases (ALDHs) in these conditions. She specializes in mass spectrometry-based omics approaches, particularly metabolomics, lipidomics, and tissue imaging mass spectrometry with a focus on MALDI techniques. Her medical research interests include Fatty Liver (Alcoholic), Genomics, Lipidomics, Mass Spectrometry, and Neurodevelopmental Disorders, while her public health interests span Behavioral Health, Biomarkers, Cancer, Genetics, Genomics, Epigenetics, Metabolism, and Metabolomics.
Dr. Charkoftaki's recent publications demonstrate a strong focus on environmental toxins, liver metabolism, and neurodevelopmental mechanisms. Her work often employs multi-omics approaches to understand complex biological systems, with particular emphasis on how environmental exposures impact human health through metabolic pathways. She has made significant contributions to understanding 1,4-dioxane toxicity, alcohol-induced liver damage, and ALDH-related mechanisms in cancer development.
Among her professional achievements, Dr. Charkoftaki was elected Secretary in 2020 and received an award from the Imaging Mass Spectrometry Society, reflecting her expertise in advanced analytical techniques.
Her collaborative research approach is evident through her extensive co-authorship network, working with researchers across multiple disciplines including toxicology, hepatology, and cancer biology. She has contributed to significant advancements in understanding the molecular mechanisms of environmental exposures and their health impacts.
Dr. Charkoftaki is actively involved with the Vasiliou Lab at Yale, which focuses on environmental health sciences and the molecular mechanisms of disease. Her work contributes to the Yale School of Public Health's mission of addressing critical public health challenges through innovative research.
