معرفی
Gary Shaw is a Professor in the Department of Biochemistry at the University of Western Ontario, affiliated with the Schulich School of Medicine and Dentistry. He serves as Director of the Biomolecular NMR Facility and employs biophysical techniques like NMR spectroscopy to study protein structure and function.
- Ubiquitin-mediated Degradation Pathways: Focus on Parkin and E2/E3 enzymes in Parkinson’s Disease.
- Calcium-binding S100 Proteins: Structural analysis of S100A10 and its role in membrane repair and trafficking.
His recent research trends span ubiquitin signaling in neurodegeneration and calcium sensor dynamics in membrane biology. Key scientific tools include structural modeling, protein interaction studies, and enzymatic assays.
The Shaw Lab investigates protein misfolding, membrane repair, and calcium-dependent signaling, with facilities like the Biomolecular NMR Facility supporting high-resolution structural analysis.
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