Gary Luker

Dr. Gary Luker is a Professor in the Department of Radiology and Biomedical Engineering at the University of Michigan Medical School. He leads the Luker Lab, focusing on molecular imaging of cell signaling in cancer, particularly breast cancer metastasis and myelofibrosis. His work integrates optical imaging, engineering, and computational modeling to study tumor microenvironment dynamics, metastatic pathways, and therapeutic resistance.

Education: M.D. from Washington University School of Medicine. Research interests span cancer biology, molecular imaging technologies (e.g., bioluminescence, fluorescence lifetime imaging), and translational medicine. Key projects include studying CXCR4 signaling pathways, mitochondrial dynamics in metastasis, and developing non-invasive MRI biomarkers for myelofibrosis treatment monitoring.

Publications emphasize metastasis mechanisms, therapeutic targeting of stromal signals, and imaging innovations. The lab collaborates across disciplines to address unmet clinical needs in cancer diagnosis and treatment.