Garrett M. Morris

Garrett M. Morris is an Associate Professor in Systems Approaches to Biomedicine at the University of Oxford, affiliated with the Department of Statistics and Green Templeton College. He holds roles as Deputy Director of Graduate Studies, Co-Director of the SABS R³ Centre for Doctoral Training, and Research Fellow at Green Templeton College. His research focuses on computational chemistry, drug discovery, and AI integration in biomedicine. He earned his DPhil from Oxford under Prof. W. Graham Richards, with subsequent work at The Scripps Research Institute and Oxford spinouts like InhibOx and Crysalin.

Research interests include protein-ligand docking, virtual screening, and machine learning applications in cheminformatics. Notable contributions include the AutoDock software and the FightAIDS@Home project. He co-organizes conferences like the Royal Society of Chemistry’s 'AI in Chemistry' and founded Comp Chem Kitchen. His lab, Oxford Protein Informatics Group (OPIG), develops novel methods for drug discovery and evaluates AI-based docking methods' validity (e.g., PoseBusters).

Recent work critiques AI docking methods' physical plausibility and generalizability. He advises numerous graduate students in statistics and drug discovery, with alumni in academia, pharma, and venture capital. Publications span molecular generation, scoring functions, and computational tools for drug design. Collaborations emphasize reproducibility, responsible research, and cloud computing in biomedicine.