معرفی
Gang Zhou is a Professor at Augusta University holding joint appointments in the Medical College of Georgia (Department of Medicine - Hematology and Oncology, Georgia Cancer Center, and Department of Biochemistry and Molecular Biology), and The Graduate School. His research focuses on the interplay between chemotherapy and cancer immunotherapy, particularly how chemotherapeutic agents modulate tumor microenvironments to enhance CD4+ T cell function. He earned his Ph.D. in Immunology from Johns Hopkins University (2003) and prior degrees in Chemistry from Fudan University (MS 1993, BS 1990).
Dr. Zhou’s lab investigates mechanisms underlying chemotherapy-induced immunosuppressive myeloid cells, tumor metabolism alterations driven by CD4+ T cells, and strategies to enhance adoptive T cell therapies. Key projects include developing non-COX inhibitory sulindac derivatives for immunomodulation and elucidating how STAT5 signaling drives T cell polyfunctionality. His work bridges immunology, oncology, and translational medicine.
Recent publications emphasize CD4+ T cell-driven antitumor immunity, microbial effects on chemoimmunotherapy efficacy, and RAS-targeted combination therapies. His research team includes postdoctoral fellows, research assistants, and undergraduate students. Dr. Zhou’s grants and collaborations support investigations into tumor recurrence mechanisms and novel therapeutic combinations.
The Zhou Lab is located at the M. Bert Storey Research Building, part of the Georgia Cancer Center. Ongoing projects aim to translate immunological insights into clinical strategies for durable cancer control.
