معرفی
Fritz Sedlazeck is an Adjunct Associate Professor at Rice University's Department of Computer Science and an Associate Professor at the Human Genome Sequencing Center (HGSC) at Baylor College of Medicine. His research focuses on algorithmic developments and high-performance computing for genomic and genetic applications, particularly structural variation (SV) detection and its implications for human diseases, cancer, and evolutionary biology. He leads the Sedlazeck Lab, which collaborates with consortia like Topmed, CCDG, and ADSP to advance genomic analysis.
Education: PhD in Computational Biology from the University of Vienna (2012) and BS in Computational Biology from FH Upper Austria (2008).
Research Interests: Structural variation (SV) origins, SV impact on complex phenotypes (e.g., neurological diseases, cancer), long-read sequencing technologies (PacBio/Nanopore), and scalable genomics pipelines. The lab develops tools like Sniffles and ngmlr for SV detection and genomic analysis.
Recent Activities: Organized the 2025 Structural Variation Hackathon and a joint lab retreat with the Treangen and Villapol labs. Focuses on advancing SV annotation, benchmarking, and clinical applications through cloud-based collaborations.
