Frederic Pouille

Frederic Pouille serves as Assistant Professor of Neuroscience (Research) in the Department of Neuroscience at Brown University, specializing in neuronal microcircuit functionality within sensory processing brain structures.

His academic credentials include:

• PhD from Université Louis Pasteur (Strasbourg I), 2002
• MS from Université Louis Pasteur (Strasbourg I), 1998

Dr. Pouille investigates neuronal microcircuits as fundamental information-processing plugins using electrophysiological, imaging, and genetic methodologies. His seminal work demonstrates how di-synaptic inhibitory circuits perform millisecond-precise operations including input desynchronization filtering, temporal fidelity preservation, saturation prevention, and frequency-specific signal modulation. These mechanisms enable extraction of meaningful information from complex neuronal spike trains within thalamocortical and hippocampal networks.

His research program examines how microcircuit operations contribute to higher cognitive functions, contextual engagement dynamics, and pathological alterations in neurological disorders—with therapeutic implications for circuit-based interventions.