Freddy Cliquet

Freddy Cliquet is a researcher at Institut Pasteur in Paris, France, specializing in autism genetics and genomics. He is actively involved in multiple research projects focused on understanding the genetic architecture of autism spectrum disorders (ASD).

His primary research interests include:

• Genetic variants associated with autism
• Phenotypic heterogeneity in autism
• Sensory processing differences in autism
• Neuroanatomical differences in autism
• Computational approaches to analyze genomic data

Cliquet has been instrumental in developing GRAVITY, a Java tool based on Cytoscape for integrating genetic variants within protein-protein interaction networks. This tool helps geneticists and clinicians identify causal variants and improve patient diagnosis. He is also involved in designing pipelines for processing and analyzing genomics data, including SNP arrays, whole-exome, and whole-genome sequencing data. His work addresses the big data challenges of managing hundreds of terabytes of genomics data.

His recent publications show a strong focus on understanding autism through multiple angles including genetic variants, sensory processing, cortical thickness, and adaptive behavior. The research often involves large-scale international collaborations such as the EU-AIMS Longitudinal European Autism Project (LEAP) and studies on the genetic architecture of autism in the Faroe Islands.

Cliquet has received recognition for his contributions to autism research through multiple high-impact publications in prestigious journals including Nature Genetics, American Journal of Psychiatry, and Molecular and Cellular Neuroscience.

He is actively involved in several ongoing projects including:

• Understanding the genetic architecture of autism in the Faroe Islands
• The IMI2 European project AIMS2-Trials
• The Paris Autism Research International Sib-Pair (PARIS) Study
• EU-AIMS project focused on developing treatments for autism