Kenneth McElreavey

Kenneth McElreavey serves as Structure Manager and Principal Investigator at Institut Pasteur in Paris, France, leading research in human developmental genetics with specialized expertise in sex determination mechanisms and Disorders/Differences of Sex Development (DSD).

His primary research interests include:

• Genetic pathways of mammalian sex determination
• Molecular basis of 46,XY gonadal dysgenesis
• Genomic variants associated with Disorders of Sex Development
• Regulatory elements in sex-determining genes like SRY
• Population genetics of DSD in North African cohorts

McElreavey's publication record from 2022-2024 reveals a research program focused on identifying novel genetic causes of DSD through exome and genome sequencing approaches, with particular emphasis on chromosomal imbalances, gene variants (SOX8, ZNRF3, HHAT, DHX37), and regulatory elements in sex determination pathways. His work bridges basic science with clinical applications through international collaborations.

As Principal Investigator of the DSD exome/genome project, he leads efforts to uncover the genetic architecture of sex development disorders using advanced genomic techniques and diverse population studies.

His laboratory operates within the Human Developmental Genetics research group at Institut Pasteur, collaborating with senior researchers including Anu Bashamboo and Denis Houzelstein, and contributing to a vibrant research environment that includes PhD students and postdoctoral fellows investigating various aspects of developmental genetics.