معرفی
Associate Professor Freda Passam is a Clinical Academic Haematologist at Royal Prince Alfred Hospital, University of Sydney, specializing in thrombosis and haemostasis. She leads the Haematology Research Group at the Charles Perkins Centre, focusing on platelet biology, endothelial cell dysfunction, and translational research in cardiovascular diseases. Her work integrates basic science with clinical applications, including developing microfluidic technologies like the Endo-chip for thrombosis diagnosis and therapy screening.
Education: MD and PhD in Greece (angiogenesis in Hodgkin’s lymphoma), postdoctoral training at UNSW and Harvard University. Research spans platelet hyperactivity in diabetes, immune thrombosis (e.g., HIT), and thiol isomerase inhibitors as antithrombotics. Collaborates globally with institutions like Harvard and the University of Utah.
Research Interests: 1) Platelet biomarkers in diabetes-related cardiovascular risk; 2) Immune thrombosis diagnostics/therapies (e.g., Endo-chip); 3) Bone marrow-on-chip models for thrombopoiesis. Current projects include SEC61B regulation of calcium flux, endothelial thromboinflammation, and ERp5/ERp57 roles in platelet production.
Grants: Over $6M in funding from NHMRC, MRFF, NSW Health, and industry partnerships. Notable awards include Sydney Nano Grand Challenge Award (2022) and SLHD VTE Stewardship Award (2020).
Advising: Mentors over 6 PhD/master’s students in thrombosis research, emphasizing clinical/research integration. Teaching includes Sydney Medicine curriculum, bedside tutorials, and student engagement in lab activities.
Labs/Teams: Haematology Research Group (Charles Perkins Centre), collaborations with Sydney Health Partners, Harvard, and international haematology groups. Develops technologies like the Endo-chip and bone marrow-on-chip models.