معرفی
Frank Sicheri is a Professor in the Departments of Biochemistry and Molecular Genetics at the University of Toronto, specializing in the structural biology of eukaryotic signal transduction. His research leverages x-ray crystallography and biochemical methods to investigate protein kinase regulation, focusing on structural mechanisms of catalytic switching, substrate recognition, and downstream phosphoregulatory processes. Recent work extends to ubiquitin-directed proteolysis, with implications for drug development targeting human diseases.
- Lab Members: Alexander Keszei, Zhiqin Li, John Li, Nero Thevakumaran, Leo Wan, Elton Zeqiraj (Graduate Students/Postdocs)
- Courses Taught: BCH 2110H Eukaryotic Signaling, BCH 2024H Eukaryotic Signaling, BCH374Y1 Research Project in Biochemistry, BCH473Y Advanced Research Project in Biochemistry
Scientific Awards: Royal Society of Canada Fellow (2011), Tier 1 Canada Research Chair (Structural Biology of Signal Transduction, 2009-present), Merck Frosst Prize (2008), Terry Fox Young Investigator Scholar (2003), National Cancer Institute of Canada Research Scientist Scholar (1999-2004), Premier’s Research Excellence Award (1998), Canada Foundation for Innovation Researcher (1998), Human Frontier Science Program Postdoctoral Fellowship (1996-1998).
