Frank R. Sharp

Frank R. Sharp, M.D., is a Professor of Neurology at the University of California Davis, affiliated with the UC Davis MIND Institute. His research focuses on brain injury mechanisms, including ischemic stroke, intracerebral hemorrhage, Alzheimer's disease, and neurodegenerative conditions, utilizing whole genome studies in humans and animal models. He has held visiting professorships at prominent institutions such as the University of Pennsylvania, UCSF, and NYU from 2012 to 2020.

• B.S., UC Davis (1968)
• M.D., UC San Diego (1972)
• Research Associate, NIH (1973-1976)
• Residency in Neurology, UCSF (1976-1979)

Dr. Sharp's research interests include stroke pathophysiology, neuroimaging biomarkers, gene expression profiling in cerebrovascular disorders, and the role of microbial molecules in Alzheimer's disease. His work integrates clinical neurology with molecular and genomic approaches to understand disease mechanisms.

His recent publications emphasize blood-based transcriptomic profiling in stroke subtypes, exploring biomarker discovery and therapeutic targets. Notable contributions include studies on vasospasm in subarachnoid hemorrhage, cancer-related stroke mechanisms, and the impact of smoking on stroke-related gene expression.

• Recipient of the Willis Award (2019)
• Dean’s Prize for Excellence in Research (2009)
• Listed among the ISI Most Highly Cited Neuroscientists (2003)

Dr. Sharp’s academic leadership includes roles as Distinguished Professor (UC Davis, 2017) and invited lecturer for international societies like the American Neurological Association and Japanese Society for Molecular Neurosurgery. His teaching excellence has been recognized multiple times.