Frank Heisler

Frank Heisler is a researcher at the Institute of Molecular Neurogenetics within the University Medical Center Hamburg-Eppendorf (UKE). His work focuses on molecular mechanisms underlying synaptic functions and neuronal transport.

• Research Unit: Institute of Molecular Neurogenetics, UKE

His research investigates how microtubule dynamics, kinesin motors, and cytoskeletal proteins like muskelin and radixin regulate synaptic plasticity and neuronal activity. Key areas include:

• Microtubule-Kinesin Transport Systems
• Dendritic Golgi Satellite Function
• AMPA and GABA_A Receptor Trafficking
• Prion Protein Targeting in Neurodegeneration
• Actin Remodeling at Synapses

Frank led the DFG-funded subproject FG 2419: HE 8413/1-1 (2019-2023) under the consortium Plasticity versus Stability - Molecular Mechanisms of Synaptic Strength. This project explored how local secretory systems in dendrites affect synaptic protein glycosylation and transport.

His publications highlight collaborations with the Neuro-Immune-Network Hamburg and interdisciplinary approaches combining molecular biology, neuroscience, and protein trafficking studies. Current work appears to focus on the interplay of cytoskeletal elements and synaptic stability.