معرفی
Francis Barany is a Professor at the Graduate School of Medical Sciences within Weill Cornell Medicine, specializing in Microbiology and Immunology. His research spans molecular profiling of cancers, development of novel diagnostic assays, and detection of infectious pathogens.
Education
- Ph.D. from The Rockefeller University (1981)
- B.A. from University of Illinois (1976)
Dr. Barany's research interests focus on identifying DNA/RNA alterations in tumors, creating coferons for protein interaction inhibition, and high-throughput pathogen detection. His work integrates genomics, epigenetics, and microfluidics to refine cancer diagnostics and therapies.
His publications highlight trends in cancer mutation analysis, epigenetic biomarkers, and molecular assay development, particularly using PCR-LDR and microarray platforms. Over 15 years, his studies have emphasized colorectal and breast cancer, viral pathogen detection, and drug resistance mechanisms.
Grants and Collaborations
- NCI Program Project Grant for comprehensive colon tumor profiling
- NIAID Collaborative Project Grants for pathogen detection
- Recent funding from Oxford Nanopore Technologies PLC and Acuamark Diagnostics
- Collaborations with Memorial Sloan Kettering, Rockefeller University, and Lawrence Livermore National Labs
Laboratory and Technology
The Barany Lab utilizes state-of-the-art equipment, including Real-time Thermocyclers, DNA array technology, and robotic workstations for high-throughput analyses. His lab is known for pioneering the ligase chain reaction (LCR), ligase detection reaction (LDR), and programmable DNA chip (Universal Array), with current projects in single-molecule sequencing and nanofabrication.
