Fleur van der Sijde

Fleur van der Sijde is a Researcher at Erasmus MC in the Department of General Practice, focusing on clinical and translational oncology, particularly in pancreatic cancer. Her work integrates immunology and molecular diagnostics to improve treatment outcomes.

Research Interests: Her research centers on understanding tumor progression, immune response modulation during chemotherapy, and identifying predictive biomarkers in pancreatic ductal adenocarcinoma. She investigates serum cytokine dynamics, gene expression profiles, and immune cell populations to determine early response to FOLFIRINOX therapy.

The recent publications show a strong trend in immuno-oncology, emphasizing the interplay between systemic immunity and chemotherapy efficacy. Her work leverages flow cytometry, transcriptomics, and clinical cohort data to uncover mechanisms of treatment resistance and survival predictors.

Scientific Contributions:

• Developed multigene circulating biomarkers for early prediction of chemotherapy response.
• Demonstrated association between cytokine levels and tumor progression/survival.
• Highlighted methodological impacts of data analysis techniques on clinical discoveries.

Advising and Grants: While no formal advisees or grant details are mentioned, her involvement in multi-center studies and doctoral thesis suggests active participation in collaborative research projects under senior supervision. She likely contributes to study design, data analysis, and manuscript preparation in high-impact oncology research.

Labs and Teams: Works within a multidisciplinary oncology research team at Erasmus MC, collaborating with experts in surgery, medical oncology, immunology, and molecular diagnostics. The team focuses on improving outcomes for pancreatic cancer patients through personalized medicine approaches.