Ellis Eikenboom

Ellis Eikenboom is a Researcher in the Department of Clinical Genetics at Erasmus University Medical Center (Erasmus MC) in Rotterdam, the Netherlands, specializing in hereditary cancer syndromes with emphasis on Lynch syndrome and DNA mismatch repair mechanisms.

Dr. Eikenboom's research focuses on Cancer Genetics and Hereditary Cancer Syndromes, particularly the molecular pathways of DNA Mismatch Repair in colorectal, endometrial, and pancreatic carcinogenesis. Current work investigates genotype-phenotype correlations in MSH6-associated Lynch syndrome, microsatellite instability patterns, and tumor behavior across multiple cancer types.

Recent publications demonstrate a strong trend toward clinical translation of genetic findings, with studies analyzing cancer survival outcomes, prevention strategies, and nationwide cohort data from the Netherlands. Research employs multidisciplinary approaches integrating surgical oncology, molecular diagnostics, and epidemiological methods to address hereditary cancer risks.

Collaborative networks include the Dutch Foundation for Detection of Hereditary Tumors, with emphasis on nationwide studies examining endometrial cancer prevention and pancreatic ductal adenocarcinoma management in Lynch syndrome patients. Current projects involve genotype-specific phenotype analysis and parent-of-origin effect studies.