A. Wagner

Dr. A. Wagner is a researcher at Erasmus MC specializing in hereditary gastrointestinal tumors. The research group focuses on diagnostics and clinical management of syndromes like Lynch syndrome and Peutz-Jeghers syndrome, collaborating with departments of Gastroenterology & Hepatology, Gynecology, and Pathology.

• Key Affiliations: Erasmus MC (Gastroenterology & Hepatology, Gynecology, Pathology), Leiden University Medical Center
• Collaborations: INVUSE consortium for MMR gene variant classification

Research interests center on improving genetic diagnostics, cancer risk estimation, and surveillance strategies for hereditary colorectal cancer syndromes. The group pioneered the LIMO study, establishing routine Lynch syndrome testing in Dutch clinical guidelines.

Recent publications highlight work on MMR mutation detection, cost-effectiveness of screening programs, and comparative imaging techniques for Peutz-Jeghers syndrome surveillance. Notable keywords include DNA repair, microsatellite instability, and population-based cancer prevention.

The group is funded through national research grants and participates in guideline development for hereditary cancer management. For inquiries, contact the Erasmus MC office via their provided form.